[ PRODUCTS / TDO ]
In validation
TDO
Therapeutic Dose Optimisation makes complex medicine dosing simpler and more precise, turning pharmacological research into practical clinical tools.
[ 01 / THE PROBLEM ]
Getting the dose right is hard.
For certain medicines, the right dose is complex to work out. Patient responses vary with kidney function, medical history and other drugs.
Clinicians often rely on incomplete data and manual calculations, which increases the risk of guesswork and human error.
[ 02 / WHAT TDO DOES ]
One workflow for dosing decisions.
TDO brings patient data, dosing history, lab results and scientific models together in a single automated digital workflow.
TDO application screen. TDO is in validation.
01
Tailored dosing
Uses each patient’s own data to model how their body handles a drug.
02
Connected data
Brings records, lab results and medications together in one place.
03
Clear visuals
Shows history, test results and projections in an easy-to-read layout.
04
Flexible design
Lets researchers update models and add new drugs over time.
[ 03 / INITIAL FOCUS ]
Starting with vancomycin.
TDO’s first application is vancomycin, a complex antibiotic with high variability between patients, including support for dialysis.
First application
High variability between patients
Includes
Dosing for patients on dialysis
Next
Other narrow-margin drugs to follow
Integration
Built to integrate with electronic medical records
[ 04 / BENEFITS ]
Safer, more precise dosing.
Dosing decisions for narrow-margin medicines get clearer and less error-prone, and the research behind them reaches routine hospital workflows.
01
Safer, more precise dosing
Doses tailored to the individual patient, for narrow-margin drugs.
02
Lower risk of adverse reactions
Reduces the risk from incorrect exposure to the drug.
03
Easier to interpret limited data
Makes sense of the few blood concentration results that are available.
04
Less manual work
Less manual maths and less data to transfer by hand.
05
Research in routine workflows
Brings research into everyday hospital workflows, seamlessly.
[ 05 / DESIGNED FOR ]
Built for the people who decide the dose.
TDO helps doctors and nurses work out safe, effective doses for individual patients, and gives researchers a way to keep the models current.
Doctors and nurses
Researchers
Built on Phycera
Part of the Phycera platform
TDO builds on Phycera’s existing technology foundation. That means faster translation of research into software, direct integration with electronic medical records, and a reusable base for future medicines.
[ 06 / WHERE IT’S UP TO ]
Moving from research to the ward.
TDO is being developed with academic and clinical experts, including Adelaide University, CALHN and expert pharmacologists. It is now in validation and is built to integrate with electronic medical records.
[ MORE FROM PHYCERA ]
Other applications on the platform.
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CCIS
Live vitals, lab results and notes in one structured chart for intensive care teams.
Learn more →
02 · In co-design
CareFlow
Near real-time visibility of patient movement, bed capacity and service pressures.
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04 · In use
Registries
Automates the preparation and submission of clinical registry data.
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05 · Market ready
CODEXA
AI-assisted clinical coding, built on Phycera for AusHealth.
Read the case study →